Adrian, over at the Coyote Within posted this series called the Breakthrough Manifesto Part 1, 2, and 3.
It's a great collection of suggestions for how to generate breakthroughs. Check it out.
A couple choice quotes:
Part 3: There are two prerequisites for breakthrough: an openness to fresh ideas and experiences; and the willingness to be changed by them. To grow and develop it's essential to let go of wherever you are now. Let the future through. Allow the universe to change you. Don't try to force it into channels you think are safe or acceptable. Breakthrough cannot come until you deliberately walk away from the comfortable and the predictable. If you lack the courage for these, you'll never make a breakthrough.
Part 2: Delight in metaphors and analogies. Every object or idea can stand for something else or suggest an unexpected link. Dull people restrict their thinking and reading to what seems obviously relevant. Clever ones peer into what isn't. You'll maybe discover far more about working life from poetry, philosophy or good novels that you ever will from business books and self-satisfied self-help writers.
Part 1: Take your mind and thinking on trips away. The world is bigger, stranger, more wonderful and less predictable than you imagine. You won't find it limited to programs on your TV, or what you can find on the Internet, or what the media present to you. Go out there and look for yourself. Deliberately step outside your comfort zone. See what you can find. You may come back a changed person. Conservatism is the philosophy of always sticking with what you have and trying to defend it against change. It's a hopeless attempt. The best, longest-lasting and most valuable ideas remain because they continually adapt to the times. Things that don't change are dead.